Emilie Bessède​

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INSERM Unit 1312

University of Bordeaux

(rez de chaussée batiment 2b zone nord)

146 rue Léo Saignat

33076 Bordeaux Cedex

tel.: +33556795667

email: emilie.bessede@u-bordeaux.fr

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Current position

Associate Professor in the Bacteriology Department of the University Hospital of Bordeaux

and in the Team 4 of INSERM Unit 1312 Bordeaux Institute of onCology (BRIC) 

 
Education & Work Experience

• 2007 Diploma of Pharmacy, University of Limoges

• 2007 Pharmacy Thesis and Medical Biology Diploma

• 2012 PhD thesis, University of Bordeaux

• 2017 Diploma for Authorisation to oversee research projects, University of Bordeaux

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Postgraduate Training

• 2002 – 2007 : Internship, University Hospital of Bordeaux

• 2005 : Master 2, Université François Rabelais, Tours

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Academic appointments

• 2008 – 2012 Assistant Professor of Bacteriology, University of Bordeaux

• since 2012 : Associate Professor of Bacteriology, University of Bordeaux

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Awards

• Best Thesis Price of Fondation de Bordeaux

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Memberships

• Member of the Groupe d’étude Français des Helicobacters (GEFH)

• Member of the Scientific Committee of the University of Bordeaux

• European Society of Clinical Microbiology and Infectious Diseases (ESCMID),

• Société Française de Microbiologie (SFM)

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Research interest

• Gastric carcinogenesis linked to H. pylori

• Gastric microbiota

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Books published

Book chapters:

• Lehours P., Mégraud F., Burucoa C., Pichon M., Bessède E. Helicobacter pylori. Chapitre 61 du REMIC, édition 2021

• Mégraud F., Bessède E., Lehours P. Diagnostic des infections à Helicobacter pylori au laboratoire. EMC Biologie médicale (Elsevier Masson SAS, Paris) 2018:1-6

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Number of Publications

• 64

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H index

• 16

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10 best publications on Helicobacter

• Bessède E, Staedel C, Acuña Amador LA, Nguyen PH, Chambonnier L, Hatakeyama M, Belleannée G, Mégraud F, Varon C. Helicobacter pylori generates cells with cancer stem cell properties via epithelial-mesenchymal transition-like changes. Oncogene. 2014 Aug 7;33(32):4123-31. doi: 10.1038/onc.2013.380.

• Bessède E, Dubus P, Mégraud F, Varon C. Helicobacter pylori infection and stem cells at the origin of gastric cancer. Oncogene. 2015 May 14;34(20):2547-55. doi: 10.1038/onc.2014.187.

• Bessède E, Molina S, Amador LA, Dubus P, Staedel C, Chambonnier L, Buissonnière A, Sifré E, Giese A, Bénéjat L, Rousseau B, Costet P, Sacks DB, Mégraud F, Varon C. Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro. Oncotarget. 2016 Dec 6;7(49):80688-80699. doi: 10.18632/oncotarget.12486.

• Mégraud F, Alix C, Charron P, Bénéjat L, Ducournau A, Bessède E, Lehours P. Survey of the antimicrobial resistance of Helicobacter pylori in France in 2018 and evolution during the previous 5 years. Helicobacter. 2021 Feb;26(1):e12767. doi: 10.1111/hel.12767.

• Courtois S, Bénéjat L, Izotte J, Mégraud F, Varon C, Lehours P, Bessède E. Metformin can inhibit Helicobacter pylori growth. Future Microbiol. 2018 Nov;13:1575-1583. doi: 10.2217/fmb-2018-0184. Epub 2018 Nov 13.

• Tiffon C, Giraud J, Molina-Castro SE, Peru S, Seeneevassen L, Sifré E, Staedel C, Bessède E, Dubus P, Mégraud F, Lehours P, Martin OCB, Varon C. TAZ Controls Helicobacter pylori-Induced Epithelial-Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties. Cells. 2020 Jun 13;9(6):1462. doi: 10.3390/cells9061462.

• Jehanne Q, Bénéjat L, Mégraud F, Bessède E, Lehours P. Evaluation of the Allplex™ H pylori and ClariR PCR Assay for Helicobacter pylori detection on gastric biopsies. Helicobacter. 2020 Aug;25(4):e12702. doi: 10.1111/hel.12702.

• Mégraud F, Bessède E. Molecular Diagnosis for Helicobacter pylori . . . at Last. Gastroenterology. 2021 Nov;161(5):1367-1369. doi: 10.1053/j.gastro.2021.08.012.

• Bénéjat L, Ducournau A, Domingues-Martins C, Lecoeur M, Blosse A, Mégraud F, Bessède E, Lehours P. Adaptation of an in-house PCR for the detection of Helicobacter pylori and the mutations associated with macrolide resistance into ready-to-use PCR microwell strips. Helicobacter. 2021 Oct 10:e12855. doi: 10.1111/hel.12855.

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