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European Registry on the management of H. pylori infection

Scientific Committee: Javier P. Gisbert, Francis Megraud, Colm O'Morain and Olga Perez Nyssen.

The great diversity of regimens and treatment lines and the different efficacy of these, requires a continuous critical analysis of clinical practice, evaluating systematically the efficacy and safety of the different regimens and diagnostic-therapeutic strategies.
The evaluation of real clinical practice using non-interventionist registries will help to improve the design and organization of European Consensus on the management of H. pylori infection, which is the best way to establish healthcare efficiency.

Primary aim

To obtain a database registering systematically a large and representative sample of routine clinical practice of European gastroenterologists in order to produce descriptive studies of the management of H. pylori infection.

Secondary aims

  • To evaluate H. pylori infection consensus and clinical guidelines implementation in different countries.

  • To perform studies focused on epidemiology, efficacy and safety of the commonly used treatments to eradicate H. pylori.

  • To evaluate accessibility to healthcare technologies and drugs used in the management of H. pylori infection.

  • To allow the development of partial and specific analysis by the participating researchers.



Optimal Management of H. pylori infection in Primary Care

H. pylori infection can be successfully managed and treated if Guidelines and Consensus Conferences are updated and implemented under the principles of Evidence Based Medicine. In this context, the aim of the present project is to continuously evaluate the input of scientific data on guidelines, the dissemination of recommendations and the implementations of guidelines in primary care. This project has been funded by an educational Grant of the United European Gastroenterology in 2013 for a period of three years.

Javier P. Gisbert, Colm O’Morain and Lars Agreus

Participant Societies:
EHMSG (European Helicobacter and Microbiota Study Group)
ESPCG (European Society for Primary Care Gastroenterology)
UEG (United European Gastroenterology)
ESGE (European Society of Gastrointestinal Endoscopy)
EAGEN (European Association for Gastroenterology, Endoscopy and Nutrition)
ESDO (European Society of Digestive Oncology)
BSG (British Society of Gastroenterology)

This project will be supported in three major areas:

Area 1: Evaluation of current evidence: A Faculty Board involving key opinion leaders from the fields of Primary Care, Gastroenterology, Public Health, Cost-effectiveness, Microbiology and Pedagogy will evaluate the current evidence regarding H. pylori infection management and the published updated guidelines in order to design the pedagogic materials and recommendations to be set in practice in the educational part of the project. The results from the European Registry on H. pylori (Parallel Project funded by the EHSG) will also be taken in consideration in order to analyse and account the current real routine clinical practice throughout Europe.

Area 2: Education and Dissemination in Primary Care: Local meetings and workshops will be organized in the different participant countries to present the conclusions by the Faculty Board and tutor the local primary care practitioners. The participants will be trained in small groups so they become tutors on their centres and health areas producing an educational cascade. An E-learning site will be set in motion in order to help and support primary care practitioners in their clinical routine. This site will also allow educational end-user to reach the primary source of the educational cascade

Area 3: Evaluation of educational impact: This project will evaluate the effect it has produced in primary care practice. The educational success will be monitored comparing pre- and post- education routine (i.e. treatments given). Medical record data monitoring or focused surveys can be used. Surveys will be sent to practitioners to evaluate the level of knowledge on, and implementation of, the guidelines 6 months after the events. Continuous monitoring of the e-training site (by feedback and site traffic) and effect on clinical practice with surveys will be performed until the end of the project. Partial and global analyses will be performed to assess the results from these actions measuring the following outcomes: participation trends, number of endoscopies and non-invasive tests, treatments given, compliance with guidelines, survey responses, knowledge-test results and cost-effectiveness analysis.

The information gathered will help design the best approach to keep primary care practitioners updated on the subject of H. pylori management.

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The EHMSG is a member of the United European Gastroenterology, a professional non-profit organisation combining all the leading European societies concerned with digestive disease.
UEG represents over 22,000 specialists, working across medicine, surgery, paediatrics, GI oncology and endoscopy. This makes UEG the most comprehensive organisation of its kind in the world, and a unique platform for collaboration and the exchange of knowledge.