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Sinead SMITH

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Ussher Assistant Professor in Applied &

Translational Medicine

Trinity College Dublin
Rm 1.46 Department of Clinical Medicine
Trinity Centre
Tallaght University Hospital
Dublin 24
Ireland

Email: smithsi@tcd.ie   

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Academic Career:

  • 2012-Present: Ussher Assistant Professor in Applied & Translational Medicine, Trinity College Dublin, Dublin, Ireland.

  • 2010-2012: Postdoctoral Researacher, Hospital for Special Surgery, New York, USA.

  • 2005-2010: Postdoctoral Researcher, Trinity College Dublin, Dublin, Ireland.

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Education:

  • 2005: PhD Cell & Molecular Biology, Dublin City University, Dublin, Ireland.

  • 1999: BSc Cell Biology & Molecular Genetics, University College Dublin, Ireland.
     

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Membership in Societies:

  • Irish Society of Gastroenterology

  • Irish Society for Immunology
     

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Research interests:​

  • H. pylori antimicrobial resistance

  • H. pylori: host interactions

  • Evaluation of novel H. pylori therapeutics

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Selected Publications:

  • Smith SM, Boyle B, Buckley M, Costigan C, Doyle M, Farrell R, Ismail MS, Kevans D, Nugent S, O'Connor A, O'Morain C, Parihar V, Ryan C, McNamara D. The second Irish Helicobacter pylori Working Group consensus for the diagnosis and treatment of Helicobacter pylori infection in adult patients in Ireland. European Journal of Gastroenterology & Hepatology 2024, 36(8): 1000-1009

  • Butler TJ, Molloy S, McNamara D, Smith SM. Diagnosis of Helicobacter pylori infection. Microbiota In Health and Disease 2023, 5: e922

  • O'Morain C, Smith SM. Antimicrobial susceptibility testing for Helicobacter pylori comes of age. The Lancet Gastroenterology and Hepatology 2023, 8(7): 593-595

  • Molloy SD, Butler TJ, Merrigan I, Knight A, Parihar V, Van Der Merwe K, McNamara D, Smith SM. Evaluation of real-time PCR compared to culture for the detection of clarithromycin resistant Helicobacter pylori in the Irish healthcare setting. Microbiota in Health and Disease 2023, 5: e956

  • Nabavi-Rad A, Sadeghi A, Aghdaei HA, Yadegar A, Smith SM, Zali MR. The double-edged sword of probiotic supplementation on gut microbiota structure in Helicobacter pylori management. Gut Microbes 2022, 14(1): 2108655

  • Brennan D, O'Morain C, McNamara D, Smith SM. Combined antrum and corpus biopsy protocol improves Helicobacter pylori culture success. World Journal of Gastrointestinal Pathophysiology 2022, 13(1): 34-40

  • Neves NCV, de Mello MP, Smith SM, Boylan F, Caliari MV, Castilho RO. Chemical composition and in vitro anti-Helicobacter pylori Activity of Campomanesia lineatifolia Ruiz & Pavón (Myrtaceae) essential oil. Plants 2022, 11(15): 1945

  • Sinead Smith. Helicobacter pylori: Methods and Protocols (Book) Springer Nature 2021

  • Zaslona Z, Flis E, Nulty C, Kearney J, Fitzgerald R, Douglas AR, McNamara D, Smith S, O'Neill LAJ, Creagh EM. Caspase-4: A therapeutic target for peptic ulcer disease. Immunohorizons 2021, 4 (10): 627-633

  • Smith SM, Freeley M, Moynagh P, Kelleher D, Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins. Helicobacter 2017, 22(1)

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All publications:

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Editorial and Review Activities:

  • 2021-present: Frontiers in Gastroenterology Editorial Board Member

  • 2020-present: Frontiers in Immunology Editorial Board Member

  • 2014-present: World Journal of Gastroenterology Editorial Board Member

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The EHMSG is a member of the United European Gastroenterology, a professional non-profit organisation combining all the leading European societies concerned with digestive disease.
UEG represents over 22,000 specialists, working across medicine, surgery, paediatrics, GI oncology and endoscopy. This makes UEG the most comprehensive organisation of its kind in the world, and a unique platform for collaboration and the exchange of knowledge.

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